Studies of Human Intestinal Absorption

Studies on the Intestinal Absorption of Tissue

I t h a s r e c e n t l y b e e n r e p o r t e d t h a t e n t e r a l a d m i n i s t r a t i o n o f t i s s u e k a l l i k r e i n (pig p a n c r e a t i c k a l l i k r e i n ) c a n have a n i m p r o v i n g e f f e c t i n s e v e r a l p a t h o l o g i c d i s o r d e r s s u c h a s an i n c r e a s e i n sperm o u t p u t and sperm m o t i l i t y i n a s t h e n o z o o s p e r m ...

Studies on intestinal absorption of sulpiride (3): intestinal absorption of sulpiride in rats.

The aim of this study was to investigate whether the concomitant administration of the substrates or inhibitors of PEPT1, OCTN1, OCTN2, and P-glycoprotein affects the intestinal absorption of sulpiride in rats. The absorption of sulpiride from rat intestine was decreased by the substrates or inhibitors of PEPT1, OCTN1, and OCTN2. On the other hand, the absorption was increased by the substrates...

Studies on Iron Absorption. Intestinal Regulatory Mechanisms.

Recent studies (1-3) have indicated that gastrointestinal absorption of iron is a more complicated process than was initially postulated (4, 5). For example, several investigators have proposed as the result of studies in rats (2, 3), dogs (6), and humans (7) that iron absorption involves at least 2 steps: 1) mucosal uptake of iron from the intestinal lumen and 2) transfer of iron from mucosal ...

Perfusion studies in relation to intestinal absorption.

Investigation of Intestinal Absorption of Pyridinones in Rat

Recently, it has been shown that a number of hydroxypyridinones such as 1,2-dimethyl-3-hydroxypyridin-4-one (L1) are useful for the treatment of iron overload in place of desferrioxamine in thalassaemic patients. In this study, the intestinal absorption (I.A.) of L1 and one of its analogues namely 2-methy-3-hydroxypyridin-4-one (L2), which possesses a higher partition coefficient (Kpart) than L...